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@SBU-BMI

Department of Biomedical Informatics

Biomedical Informatics, Stony Brook University

Open-source tools for computational pathology: whole slide image (WSI) analysis, deep learning for histopathology, and the QuIP platform for storing, viewing, and sharing results.

Website: bmi.stonybrookmedicine.edu

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Repo What it is
wsinfer Patch-based classification pipeline for whole slide images. Pretrained models in wsinfer-zoo.
champkit Benchmarking toolkit for patch-based histopathology image classification.
SpinPath CLI for specimen-level inference on whole slide images.
quip_distro Docker Compose distribution of the QuIP platform: caMicroscope viewer, PathDB, and analysis services.
PathDB Image and annotation database behind QuIP.

Analysis models

Repo What it is
quip_cnn_segmentation CNN nucleus segmentation.
quip_cancer_segmentation Tumor region segmentation.
quip_classification Patch classification models.
u24_lymphocyte Tumor-infiltrating lymphocyte (TIL) detection.
quip_paad_cancer_detection, quip_prad_cancer_detection, quip_lung_cancer_detection Cancer-type-specific detection models.
histopathology_analysis Deep learning methods for histopathology image analysis.
deep_survival_analysis, tumor-til-survival-analysis Survival analysis from image features.

QuIP utilities

Repo What it is
cancer-data-bridge REST API bridging caMicroscope, 3D Slicer, and MongoDB.
findapi Minimal REST interface to MongoDB collections.
SegmentationLoader Load WSI segmentations into MongoDB.
featuremap_util Convert prediction outputs into PathDB featuremaps.
manifest_util Generate upload manifests for PathDB.
quip_reports Export image and annotation inventory reports.
quip_converter Convert vendor slide formats to tiled multiresolution TIFF.

Other

Repo What it is
SlicerPathology 3D Slicer extension for pathology segmentation.
nscale High-performance image analysis libraries (C++, MPI).
region-templates Region Templates runtime for large-scale image analysis.
MappingOHDSI2HDF5 JSON mappings from OHDSI tables to HDF5.

Funding

This work is supported by NCI U24 and related awards. See individual repositories for grant acknowledgements.

License

Most repositories are released under the BSD 3-Clause License. Check each repository's LICENSE file.


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